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Persistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis

We report on a Ph+ chronic myelocytic leukemia (CML) case, cytogenetically characterized by the occurrence of a second Philadelphia (Ph) chromosome in lymphoid blast crisis of T cell lineage. In situ hybridization analyses showed a deletion of translocated c-abl sequences, present on the Ph during c...

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Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1986
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188457/
https://ncbi.nlm.nih.gov/pubmed/3464689
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