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Cyclosporine-induced autoimmunity. Conditions for expressing disease, requirement for intact thymus, and potency estimates of autoimmune lymphocytes in drug-treated rats

These studies explore the phenomenon of cyclosporine-induced autoimmunity in irradiated Lewis rats. We show that (a) the presence of a thymus is required, and autoimmune precursors develop in and exit from this organ to the peripheral lymphocyte pool within a 2-wk period after the initiation of cycl...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188452/
https://ncbi.nlm.nih.gov/pubmed/3490534
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