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Effect of gamma interferon on cachectin expression by mononuclear phagocytes. Reversal of the lpsd (endotoxin resistance) phenotype

IFN-gamma permits the endotoxin-induced production of cachectin by C3H/HeJ (endotoxin resistant) macrophages, apparently by facilitating endotoxin-induced cachectin biosynthesis at both transcriptional and posttranscriptional levels. IFN-gamma cannot induce cachectin biosynthesis by itself, nor does...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1986
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188450/
https://ncbi.nlm.nih.gov/pubmed/3095481
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