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Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential

Lethal infections are associated with cellular dysfunction as evidenced by a decrease in the resting transmembrane potential difference (Em) of skeletal muscle fibers. Endotoxin stimulation of macrophages evokes production of cachectin, a protein that has been implicated as a mediator of the lethal...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188416/
https://ncbi.nlm.nih.gov/pubmed/3760781
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