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Systemic autoimmune disease arises from polyclonal B cell activation

The number of B cells producing antibodies reactive with any of seven autoantigens or two conventional antigens was compared at the single- cell level to the total number of Ig-secreting B cells present in the spleens of NZB, MRL lpr/lpr, and BXSB autoimmune mice. The proportion of lymphocytes produ...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1987
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188353/
https://ncbi.nlm.nih.gov/pubmed/3495631
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