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Idiotypic self binding of a dominant germline idiotype (T15). Autobody activity is affected by antibody valency
We have previously described (1-3) an IgM antibody that binds to PC, expresses the T15 idiotype, and binds also to itself or T15 if insolubilized. Because of the simultaneous presence of complementary idiotopes and paratopes this type of antibody has been termed autobody. The self binding involves t...
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| Format: | Artigo |
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| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
1987
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188311/ https://ncbi.nlm.nih.gov/pubmed/3106554 |
| Oznake: |
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