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Administration of recombinant interleukin 2 in vivo induces a polyclonal IgM response

We studied the potential immunoenhancing effects of high doses of rIL-2 on murine T and B cell functions in vivo. Injection of rIL-2 caused a threefold or more increase in the frequencies of antigen-specific proliferative T cells, suggesting that rIL-2 initiated a polyclonal T cell response. In prim...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188122/
https://ncbi.nlm.nih.gov/pubmed/3486940
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