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Destruction of Leishmania mexicana amazonensis amastigotes within macrophages by lysosomotropic amino acid esters

Leishmania amastigotes parasitize almost exclusively the mononuclear phagocytes of mammals. The organisms survive and multiply within acidified vacuoles (parasitophorous vacuoles; p.v.) akin to phagolysosomes. Certain amino acid esters are known to accumulate in and disrupt lysosomes. We postulated...

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Bibliografske podrobnosti
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1986
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188052/
https://ncbi.nlm.nih.gov/pubmed/3950542
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