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Evidence for sequential signals in the induction of the arachidonic acid cascade in macrophages

We have examined the requirement for Na+, Ca2+, and protein synthesis in the induction of the arachidonic acid (20:4) cascade in cultured murine peritoneal macrophages. Replacement of extracellular Na+ with choline or with K+ inhibited receptor-mediated 20:4 release by 60-90%, but did not inhibit re...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188017/
https://ncbi.nlm.nih.gov/pubmed/2416865
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