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Monoclonal antibody to Theiler's murine encephalomyelitis virus defines a determinant on myelin and oligodendrocytes, and augments demyelination in experimental allergic encephalomyelitis

Theiler's murine encephalomyelitis virus (TMEV) causes a chronic demyelinating disease in mice. The mechanisms underlying the demyelination have not been fully elucidated. We have raised a mAb to TMEV (DA strain), H8, that reacts both with TMEV VP-1 and galactocerebroside (GC). In mouse brain c...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187947/
https://ncbi.nlm.nih.gov/pubmed/1693653
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