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Acute lethal graft-versus-host reaction induced by major histocompatibility complex class II-reactive T helper cell clones
T cell clones isolated from class II MHC-disparate MLR combinations, and specific for I-Ak and I-Ek molecules, respectively, are shown to induce acute lethal graft-vs-host disease in unirradiated recipients. Cytolytic and noncytolytic clones are equally efficient in this respect. The lethal disease...
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| Format: | Artigo |
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| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2187885/ https://ncbi.nlm.nih.gov/pubmed/2139696 |
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