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Acute lethal graft-versus-host reaction induced by major histocompatibility complex class II-reactive T helper cell clones

T cell clones isolated from class II MHC-disparate MLR combinations, and specific for I-Ak and I-Ek molecules, respectively, are shown to induce acute lethal graft-vs-host disease in unirradiated recipients. Cytolytic and noncytolytic clones are equally efficient in this respect. The lethal disease...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187885/
https://ncbi.nlm.nih.gov/pubmed/2139696
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