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Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level [published erratum appears in J Exp Med 1990 Mar 1;171(3):971-2]
The biosynthesis of cachectin/TNF is largely regulated at a post- transcriptional level. Bacterial endotoxin, which strongly induces cachectin/TNF production, thus seems to elicit at least some of its effects by altering the macrophage cytoplasmic milieu. It has previously been shown that the 3'...
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| Format: | Artigo |
|---|---|
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
1990
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2187716/ https://ncbi.nlm.nih.gov/pubmed/2303781 |
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