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Origins of mitochondrial thymidine triphosphate: Dynamic relations to cytosolic pools

Nuclear and mitochondrial (mt) DNA replication occur within two physically separated compartments and on different time scales. Both require a balanced supply of dNTPs. During S phase, dNTPs for nuclear DNA are synthesized de novo from ribonucleotides and by salvage of thymidine in the cytosol. Mito...

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Autori principali: Pontarin, Giovanna, Gallinaro, Lisa, Ferraro, Paola, Reichard, Peter, Bianchi, Vera
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC218729/
https://ncbi.nlm.nih.gov/pubmed/14519855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1635259100
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