Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

This report describes an unbiased method for systematically determining gene function in mammalian cells. A total of 20,704 predicted human full-length cDNAs were tested for induction of the IL-8 promoter. A number of genes, including those for cytokines, receptors, adapters, kinases, and transcript...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Iourgenko, Vadim, Zhang, Wenjun, Mickanin, Craig, Daly, Ira, Jiang, Can, Hexham, Jonathan M., Orth, Anthony P., Miraglia, Loren, Meltzer, Jodi, Garza, Dan, Chirn, Gung-Wei, McWhinnie, Elizabeth, Cohen, Dalia, Skelton, Joanne, Terry, Robert, Yu, Yang, Bodian, Dale, Buxton, Frank P., Zhu, Jian, Song, Chuanzheng, Labow, Mark A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1932773100
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