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Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains

Using a cloned cDNA of a mouse immunoglobulin kappa light chain synthesized in a myeloma MOPC321 (V kappa-21 subgroup C) as a probe we could detect 13 germ line V kappa gene segments. 11 of these were isolated. Using a set of overlapping cloned segments, we showed that nine of these germ line V kapp...

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Bibliographische Detailangaben
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1984
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187233/
https://ncbi.nlm.nih.gov/pubmed/6420501
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