Loading...

Neonatal tolerance of major histocompatibility complex antigens alters Ir gene control of the cytotoxic T cell response to vaccinia virus

The K region of H-2 controls the Tc cell response to vaccinia-Db. The Kb, Kd, and Kq alleles allow good Tc cell responses against vaccinia- Db. In contrast, the presence of Kk in H-2 recombinants 2R (Kk,Db) and 4R (Kk,Db) or in F1 hybrids greatly reduces the anti-vaccinia-Db response. The defect doe...

Full description

Saved in:
Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186975/
https://ncbi.nlm.nih.gov/pubmed/6220111
Tags: Add Tag
No Tags, Be the first to tag this record!