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Mutant monoclonal antibodies with alterations in biological functions

Somatic cell mutants with deletions in the immunoglobulin constant region were isolated from an IgG(2b) Ar-binding hybridoma. Rat anti-mouse immunoglobulins were used to identify the sites of the deletions. The mutant monoclonal antibodies differ from the parental molecule in their assembly states a...

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Bibliografiske detaljer
Main Authors: Yelton, DE, Scharff, MD
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186830/
https://ncbi.nlm.nih.gov/pubmed/6818317
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