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Generation of cytolytic T lymphocytes in thymectomized, irradiated, and bone marrow-reconstituted mice

A model system has been developed to study extrathymic T cell differentiation. Mice have been thymectomized, lethally irradiated, and reconstituted with bone marrow cells depleted of Thy-1-positive cells. After 8 wk, the spleen cells of these 5athymic, bone marrow- reconstituted chimeras contain Thy...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186799/
https://ncbi.nlm.nih.gov/pubmed/6125557
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