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J chain is encoded by a single gene unlinked to other immunoglobulin structural genes

Immunoglobulin J chain mediates the polymerization of both IgM and IgA immunoglobulins. Its synthesis is closely regulated in B lymphocytes, apparently at the level of RNA transcription. To define the genetic bases of this regulation, we have determined the location and number of J chain genes in th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1982
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186616/
https://ncbi.nlm.nih.gov/pubmed/6278047
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