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Roles of adjuvant and route of vaccination in antibody response and protection engendered by a synthetic matrix protein 2-based influenza A virus vaccine in the mouse

BACKGROUND: The M2 ectodomain (M2e) of influenza A virus (IAV) strains that have circulated in humans during the past 90 years shows remarkably little structural diversity. Since M2e-specific antibodies (Abs) are capable of restricting IAV replication in vivo but are present only at minimal concentr...

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Detalhes bibliográficos
Main Authors: Mozdzanowska, Krystyna, Zharikova, Darya, Cudic, Mare, Otvos, Laszlo, Gerhard, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186315/
https://ncbi.nlm.nih.gov/pubmed/17974006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-118
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