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Expression of leukemogenic recombinant viruses associated with a recessive gene in HRS/J mice

HRS/J inbred mice carry a mutant autosomal recessive gene (hr), which in homozygotes coincides with susceptibility to spontaneous thymic leukemia. Unlike their heterozygote (hr/+) littermates, hr/hr homozygotes express high levels of xenotropic virus during the preleukemic period, and viruses with a...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1980
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185945/
https://ncbi.nlm.nih.gov/pubmed/7400758
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