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Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels

Most mammalian cell types, including endothelial cells, respond to cell swelling by activating a Cl(−) current termed I(Cl,swell), but it is not known how the physical stimulus of cell swelling is transferred to the channels underlying I(Cl,swell). We have investigated the precise relation between c...

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Autors principals: Voets, Thomas, Droogmans, Guy, Raskin, Gert, Eggermont, Jan, Nilius, Bernd
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21858/
https://ncbi.nlm.nih.gov/pubmed/10220460
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