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Quantitative studies on the precursors of cytotoxic lymphocytes. VI. Second signal requirements of specifically activated precursors isolated 12 h after stimulation

It is shown that, in a mixed lymphocyte reaction, the production of cytotoxic T lymphocytes (CL) from cytotoxic T lymphocyte precursors (CLP) requires two signals which are separated time. Using a flow cytometer-cell sorter and a vital, fluorescent DNA stain, Hoechst 3342, CLP specific for the stimu...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185751/
https://ncbi.nlm.nih.gov/pubmed/6965304
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