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T-suppressor cells sensitive to cyclophosphamide and to its in vitro active derivative 4-hydroperoxycyclophosphamide control the mitogenic response of murine splenic B cells to dextran sulfate. A direct proof for different sensitivities of lymphocyte subsets to cyclophosphamide

As measured by [(3)H]thymidine uptake, spleen cells of mice injected 7 d previously with a single dose of cyclophosphamide (Cy) (125 mg x kg (-1)) gave an enhanced response to dextran sulfate (DS), a diminished response to lipopolysaccharide (LPS), and a normal response to concanavalin A. Addition o...

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Bibliografiset tiedot
Päätekijät: Diamantstein, T, Willinger, E, Reiman, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 1979
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185724/
https://ncbi.nlm.nih.gov/pubmed/159940
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