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Mice whose B cells cannot produce the T15 idiotype also lack an antigen- specific helper T cell required for T15 expression
The X-linked CBA/N defect in B cell function precludes an antibody response to phosphorylcholine (PC). Accordingly, (CBA/N X BALB/c)F1 male mice are unresponsive to PC and lack circulating immunoglobulin bearing the T15 idiotype characteristic of BALB/C anti-PC antibody. In contrast, (CBA/N X BALB/c...
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| Формат: | Artigo |
|---|---|
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
1979
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2185721/ https://ncbi.nlm.nih.gov/pubmed/92522 |
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