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Differential effect of hydroxyurea on the replication of plasmid and chromosomal DNA in Bacillus subtilis.

The replication in Bacillus subtilis of the staphylococcal R plasmids pE194, pBD15, pUB110, pSA0501, and pSA2100 has been studied in the presence of hydroxyurea. In all cases, an enrichment for covalently closed circular DNA compared with chromosomal DNA was observed. In this respect, hydroxyurea mi...

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Bibliographic Details
Main Authors: Shivakumar, A G, Dubnau, D
Format: Artigo
Language:Inglês
Published: 1978
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC218561/
https://ncbi.nlm.nih.gov/pubmed/102636
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