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Trafficking of an Acylated Cytosolic Protein: Newly Synthesized p56(lck) Travels to the Plasma Membrane via the Exocytic Pathway

The Src-related tyrosine kinase p56(lck) (Lck) is primarily expressed in T lymphocytes where it localizes to the cytosolic side of the plasma membrane and associates with the T cell coreceptors CD4 and CD8. As a model for acylated proteins, we studied how this localization of Lck is achieved. We fol...

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Bibliografiske detaljer
Main Authors: Bijlmakers, Marie-José J.E., Marsh, Mark
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185081/
https://ncbi.nlm.nih.gov/pubmed/10225948
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