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Mechanisms of idiotype suppression. I. In vitro generation of idiotype- specific suppressor T cells by anti-idiotype antibodies and specific antigen

Normal BALB/c spleen cells are unresponsive in vitro to the phosphorylcholine (PC) determinant in the presence of anti-idiotype antibodies specific for the TEPC-15 myeloma protein (T15) which carries an idiotypic determinant indistinguishable from that of most anti-PC antibodies in BALB/c mice. The...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1979
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2184896/
https://ncbi.nlm.nih.gov/pubmed/87488
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