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A first-generation packaging cell line for Epstein–Barr virus-derived vectors

On the basis of the B lymphotropic Epstein–Barr virus (EBV), we have constructed a virus-free packaging cell line that allows encapsidation of plasmids into herpesvirus particles. This cell line harbors an EBV mutant whose packaging signals have been deleted. The gene vectors, which can encompass ve...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Delecluse, Henri-Jacques, Pich, Dagmar, Hilsendegen, Tanja, Baum, Christopher, Hammerschmidt, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21839/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220441/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5188
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