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High and selective resistance to mecillinam in adenylate cyclase-deficient or cyclic adenosine 3',5'-monophosphate receptor protein-deficient mutants of Escherichia coli.

Adenylate cyclase-deficient (cya) mutants of Escherichia coli K-12 were selectively and highly resistant to mecillinam (FL1060) among several beta-lactam antibiotics in the absence of cyclic adenosine 3',5'-monophosphate (cAMP). They became sensitive to the drug in the presence of cAMP. Also, cAMP r...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Aono, R, Yamasaki, M, Tamura, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/217866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.137.2.839-845.1979
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