The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis

In a genetic screen for mutations that restrict cell growth and organ size, we identified a new tumor suppressor gene, dMST, which encodes the Drosophila homolog of the mammalian Ste20 kinase family members MST1 and MST2. Loss-of-function mutations in dMST result in overgrown tissues containing more...

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Detalles Bibliográficos

Publicado en:	Genes Dev
Autores principales:	Jia, Jianhang, Zhang, Wensheng, Wang, Bing, Trinko, Richard, Jiang, Jin
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Cold Spring Harbor Laboratory Press 2003
Materias:	Research Communications
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14561774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1134003
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