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Model of the Brain Tumor–Pumilio translation repressor complex

The Brain Tumor (Brat) protein is recruited to the 3′ untranslated region (UTR) of hunchback mRNA to regulate its translation. Recruitment is mediated by interactions between the Pumilio RNA-binding Puf repeats and the NHL domain of Brat, a conserved structural motif present in a large family of gro...

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Bibliografske podrobnosti
Main Authors: Edwards, Thomas A., Wilkinson, Brian D., Wharton, Robin P., Aggarwal, Aneel K.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC218144/
https://ncbi.nlm.nih.gov/pubmed/14561773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1119403
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