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Model of the Brain Tumor–Pumilio translation repressor complex

The Brain Tumor (Brat) protein is recruited to the 3′ untranslated region (UTR) of hunchback mRNA to regulate its translation. Recruitment is mediated by interactions between the Pumilio RNA-binding Puf repeats and the NHL domain of Brat, a conserved structural motif present in a large family of gro...

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Detalhes bibliográficos
Main Authors: Edwards, Thomas A., Wilkinson, Brian D., Wharton, Robin P., Aggarwal, Aneel K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC218144/
https://ncbi.nlm.nih.gov/pubmed/14561773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1119403
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