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Frequencies of mitogen-reactive B cells in the mouse. II. Frequencies of B cells producing antibodies which lyse sheep or horse erythrocytes, and trinitrophenylated or nitrodophenylated sheep erythrocytes

The B-cell mitogens LPS and lipoprotein stimulate 20-35 percent of all B cells in the spleen of 6- to 8-wk old C3H/Tif mice, as determined by limiting dilution analysis of precursors. Each reactive cell grows to a clone of IgM-secreting PFC, enumerated in a hemolytic plaque assay detecting all IgM s...

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Bibliografski detalji
Glavni autori: Andersson, J, Coutinho, A, Melchers, F
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1977
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180691/
https://ncbi.nlm.nih.gov/pubmed/325169
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