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RECOMBINATION OF HEAVY AND LIGHT CHAINS OF HUMAN γA-MYELOMA PROTEINS: FORMATION OF HYBRID MOLECULES AND CONFIGURATIONAL SPECIFICITY

The present studies demonstrate that the conditions necessary for reductive cleavage, isolation, and recombination of L and H polypeptide chains of human γA-myeloma globulins parallel those required for similar manipulation of the component chains of γG-globulin. Specificity of recombination was sho...

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Bibliographic Details
Main Authors: Prendergast, Robert A., Grey, Howard M., Kunkel, Henry G.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1966
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180477/
https://ncbi.nlm.nih.gov/pubmed/4162153
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