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Inhibition of tumor necrosis factor alpha secretion in rat Kupffer cells by siRNA: In vivo efficacy of siRNA-liposomes

Tumor necrosis factor alpha (TNF-α), a pro-inflammatory cytokine, plays a key role in the pathogenesis of many inflammatory diseases, including alcoholic liver disease. In the liver, Kupffer cells are the primary source of the cytokine. Obliteration of Kupffer cells or neutralization of TNF-α by ant...

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Detaylı Bibliyografya
Asıl Yazarlar: Jing, Yawu, Shishkov, Andrei, Ponnappa, Biddanda C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180390/
https://ncbi.nlm.nih.gov/pubmed/17964727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2007.09.015
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