Colorectal Cancer Risks in Relatives of Young-Onset Cases: Is Risk the Same Across All First Degree Relatives?

BACKGROUND AND AIMS: In the last fifteen years, several single-gene Mendelian disorders have been discovered that may account for some of the familial aggregation detected in large population studies of colorectal cancer (CRC). Mutations in DNA mismatch repair (MMR) genes cause HNPCC-Lynch Syndrome,...

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Detalhes bibliográficos
Main Authors: Boardman, Lisa A., Morlan, Bruce W., Rabe, Kari G., Petersen, Gloria M., Lindor, Noralane M., Nigon, Sandra K, Goldberg, Julia, Gallinger, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180165/
https://ncbi.nlm.nih.gov/pubmed/17702662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2007.06.001
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