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Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages by production of peroxynitrite

We have previously shown that surfactant protein A (SP-A) mediates in vitro killing of mycoplasmas by alveolar macrophages (AMs) from resistant C57BL/6 mice through a nitric oxide (⋅NO)-dependent mechanism. Herein, SP-A-deficient [SP-A(−/−)] and inducible ⋅NO synthase-deficient [iNOS(−/−)] mice were...

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Detalhes bibliográficos
Main Authors: Hickman-Davis, Judy, Gibbs-Erwin, Julie, Lindsey, J. Russell, Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21798/
https://ncbi.nlm.nih.gov/pubmed/10220400
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