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T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant β-catenin
N-terminal mutations in β-catenin that inhibit β-catenin degradation are found in primary tumors and cancer cell lines, and increased β-catenin/T cell factor (TCF)-activated transcription in these cells has been correlated with cancer formation. However, the role of mutant β-catenin in cell transfor...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21797/ https://ncbi.nlm.nih.gov/pubmed/10220399 |
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