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Physical evidence for a phosphorylation-dependent conformational change in the enhancer-binding protein NtrC

The bacterial enhancer-binding protein nitrogen regulatory protein C (NtrC) activates transcription by σ(54)-containing RNA polymerase in a reaction that depends on ATP hydrolysis. Phosphorylation of an aspartate residue in the N-terminal receiver domain of NtrC induces oligomerization of the protei...

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Main Authors: Hwang, Ingyu, Thorgeirsson, Thorgeir, Lee, Jonghui, Kustu, Sydney, Shin, Yeon-Kyun
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC21785/
https://ncbi.nlm.nih.gov/pubmed/10220387
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