Dedifferentiation of adenocarcinomas by activation of phosphatidylinositol 3-kinase

Signet ring cell carcinoma is a malignant type of poorly differentiated adenocarcinomas in stomach, which is characterized by the occasional presence of signet ring-like cancer cells. We found that expression of constitutively active phosphatidylinositol 3-kinase (PI 3-kinase) in well differentiated...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Kobayashi, Michimoto, Nagata, Satoshi, Iwasaki, Takuya, Yanagihara, Kazuyoshi, Saitoh, Izumu, Karouji, Yutaka, Ihara, Sayoko, Fukui, Yasuhisa
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21784/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220386/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.4874
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