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Cloning of a pleiotropic gene that positively controls biosynthesis of A-factor, actinorhodin, and prodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans.

A-factor (2S-isocapryloyl-3S-hydroxymethyl-gamma-butyrolactone), an autoregulating factor originally found in Streptomyces griseus, is involved in streptomycin biosynthesis and cell differentiation in this organism. A-factor production is widely distributed among actinomycetes, including Streptomyce...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Horinouchi, S, Hara, O, Beppu, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC217821/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6309746/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.155.3.1238-1248.1983
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