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Autoinducer binding by the quorum-sensing regulator TraR increases affinity for target promoters in vitro and decreases TraR turnover rates in whole cells

TraR is an Agrobacterium transcriptional regulator whose activity requires the pheromone N-3-oxooctanoyl-l-homoserine lactone. TraR was purified as a complex with the pheromone and contained one pheromone molecule per protein monomer. TraR–pheromone complexes bound to a single DNA site and activated...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Zhu, Jun, Winans, Stephen C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21777/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.4832
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