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A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: Biochemical identification using Xenopus egg extracts

Cellular differentiation is a complex process involving growth arrest, exit from the cell cycle, and expression of differentiated cell-type-specific functions. To identify small molecules promoting this process, a chemical library was screened by using a myeloid leukemic cell line that retained the...

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Autori principali: Rosania, Gustavo R., Merlie, John, Gray, Nathanael, Chang, Young-Tae, Schultz, Peter G., Heald, Rebecca
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21771/
https://ncbi.nlm.nih.gov/pubmed/10220373
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