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Requirement for a second sterol biosynthetic mutation for viability of a sterol C-14 demethylation defect in Saccharomyces cerevisiae.

Genetic analysis of a nystatin-resistant sterol mutant (strain JR4) of Saccharomyces cerevisiae defective in C-14 demethylation revealed the presence of a second mutation in 5,6-desaturation. It appeared from complementation tests that a defect in delta 5-desaturase enzyme activity was required for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Taylor, F R, Rodriguez, R J, Parks, L W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC217652/
https://ncbi.nlm.nih.gov/pubmed/6345514
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