Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes

Phosphatidylinositol-4,5-bisphosphate (PIP(2)) is an abundant phospholipid that contributes to second messenger formation and has also been shown to contribute to the regulation of cytoskeletal dynamics in all eukaryotic cells. Although the α, β, and γ isoforms of phosphatidylinositol-4-phosphate-5-...

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Bibliographic Details
Main Authors: Wang, Yanfeng, Litvinov, Rustem I., Chen, Xinsheng, Bach, Tami L., Lian, Lurong, Petrich, Brian G., Monkley, Susan J., Critchley, David R., Sasaki, Takehiko, Birnbaum, Morris J., Weisel, John W., Hartwig, John, Abrams, Charles S.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176194/
https://ncbi.nlm.nih.gov/pubmed/18188447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34239
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