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Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice

Myocardin (Myocd) is a potent transcriptional coactivator that has been implicated in cardiovascular development and adaptation of the cardiovascular system to hemodynamic stress. To determine the function of myocardin in the developing cardiovascular system, Myocd(F/F)/Wnt1-Cre(+) and Myocd(F/F)/Pa...

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Autors principals: Huang, Jianhe, Cheng, Lan, Li, Jian, Chen, Mary, Zhou, Deying, Lu, Min Min, Proweller, Aaron, Epstein, Jonathan A., Parmacek, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176191/
https://ncbi.nlm.nih.gov/pubmed/18188448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33304
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