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Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice

Mitochondrial dysfunction in skeletal muscle has been implicated in the development of type 2 diabetes. However, whether these changes are a cause or a consequence of insulin resistance is not clear. We investigated the structure and function of muscle mitochondria during the development of insulin...

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Detalhes bibliográficos
Main Authors: Bonnard, Charlotte, Durand, Annie, Peyrol, Simone, Chanseaume, Emilie, Chauvin, Marie-Agnes, Morio, Béatrice, Vidal, Hubert, Rieusset, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176186/
https://ncbi.nlm.nih.gov/pubmed/18188455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32601
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