Collagen I Promotes Epithelial-to-Mesenchymal Transition in Lung Cancer Cells via Transforming Growth Factor–β Signaling

Epithelial-to-mesenchymal transition (EMT) is a fundamental biological process whereby epithelial cells lose their polarity and undergo a transition to a mesenchymal phenotype. When cancer cells invade adjacent tissues, they use a mechanism akin to EMT, and understanding the molecular mechanisms tha...

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Detalhes bibliográficos
Main Authors: Shintani, Yasushi, Maeda, Masato, Chaika, Nina, Johnson, Keith R., Wheelock, Margaret J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176131/
https://ncbi.nlm.nih.gov/pubmed/17673689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0071OC
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