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Molecular Pathogenesis of Lymphangioleiomyomatosis: Lessons Learned from Orphans

Lymphangioleiomyomatosis (LAM) is a rare progressive cystic lung disease affecting young women. The pivotal observation that LAM occurs both spontaneously and as part of the tuberous sclerosis complex (TSC) led to the hypothesis that these disorders share common genetic and pathogenetic mechanisms....

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Detalhes bibliográficos
Main Authors: Juvet, Stephen C., McCormack, Francis X., Kwiatkowski, David J., Downey, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176113/
https://ncbi.nlm.nih.gov/pubmed/17099139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0372TR
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