Specific inhibition of leukotriene B4 (LTB4)-induced neutrophil emigration by 20-hydroxy LTB4: implications for the regulation of inflammatory responses.

1. The interaction between leukotriene B4 (LTB4) and its metabolite, 20-hydroxy LTB4 in the control of neutrophil emigration was examined in guinea-pig skin. 2. Leukotriene B4 (10-300 ng) elicited a dose-dependent increase in neutrophil infiltration (as measured by myeloperoxidase activity) 4 h afte...

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Main Authors: Pettipher, E. R., Salter, E. D., Breslow, R., Raycroft, L., Showell, H. J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176035/
https://ncbi.nlm.nih.gov/pubmed/8220903
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